Microfluidic rotary valves are essential components in modern fluidic systems, offering precise control over the flow of liquids through multiple channels. Microfluidic distribution valves are designed to enable efficient routing of liquids between pathways, allowing the sequential delivery of fluids in applications ranging from chemical analysis to biological experiments. Their ability to manage liquid flow with minimal internal volume and low dead volume makes them ideal for processes that require high precision.
In the world of microfluidic devices, rotary valves are the gatekeepers for directing and regulating the flow of fluids. The microfluidic distribution rotary valve, in particular, plays a critical role in the automation of fluidic processes.
Microfluidic distribution valves are designed to direct fluids through various pathways with incredible accuracy, ensuring optimal performance across diverse applications. These valves enable automation in fluid handling, providing a tool that allows for the precise injection and control of liquids within laboratory and industrial instruments. This precision is essential in fields such as biology, chemistry, and diagnostic testing, where the timing and regulation of fluid movement are critical.
AMF’s standard microfluidic distribution rotary valves are available in configurations ranging from 6 to 24 ports. These designs feature one axial port entry on the front and up to 24 radial ports. Customization options allow for configurations with fewer than 6 or more than 24 ports, catering to specific project requirements.
This process ensures that each fluid is routed precisely, supporting a wide variety of applications that demand accurate fluid control.
AMF’s microfluidic distribution valves are crafted with precision and efficiency at their core, providing unparalleled versatility and adaptability across a broad range of applications.
Users can easily adjust the valves for various flow rates and sequences, ensuring accurate results and optimal process efficiency in any setup. Additionally, AMF thoroughly evaluates each project to determine the best material for the application. Whether it’s PEEK, PTFE, PCTFE, or UHMW–PE, we offer the widest range of material options for microfluidic distribution rotary valves.
These valves seamlessly integrate into microfluidic systems, ensuring smooth fluid management while minimizing flow rate variations and providing precise flow measurement, making them an essential tool for any fluidic process.
AMF’s microfluidic distribution valves are designed to meet the rigorous demands of a wide range of applications, from lab-on-a-chip systems to high-throughput industrial processes. Their adaptability and high performance stem from specific design features that optimize fluid management under diverse conditions.
To make it easier to understand our product offerings, here is a breakdown of the nomenclature used for our valves:
V-A-B-C-D-E-F (e.g. V-D-1-5-050-C-P)
Now that you’re familiar with our coding system, here are some specific configurations and their performance details:
AMF’s microfluidic distribution valves are designed for easy and seamless integration with our core systems: the RVM Industrial Microfluidic Rotary Valve, the SPM Industrial Programmable Syringe Pump, and the LSPone Laboratory Programmable Syringe Pump. Each of these components is engineered to work harmoniously with our valves, offering users a streamlined experience in both installation and operation.
Example of use of a microfluidic distribution rotary valve with the RVM:
Maël Arveiler, Stephanie Ognier, Olivier Venier, Laurent Schiob and Michael Tatoulian – An innovative sequential flow platform for automated multi-step chemical processes – proof of concept with the separation of amine/alkene model mixtures – Reaction Chemistry & Engineering – Issue 11, 2023
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This integration ensures that even the smallest volumes are dispensed accurately, which is critical in industries such as pharmaceuticals, biotechnology, and chemical processing, where precise liquid handling is essential for product consistency and experimental accuracy.
Example of use of a microfluidic distribution rotary valve with an SPM:
The flexibility of the LSPone system, combined with AMF’s valves, makes it the perfect solution for customized microfluidic applications. Whether it’s for research or industrial production, the LSPone system ensures seamless, automated fluid handling, improving workflow consistency and reducing the risk of human error.
Example of use of a microfluidic distribution rotary valve with a LSPone:
Xiaokang Li, Hui Song Pak, Florian Huber, Justine Michaux, Marie Taillandier-Coindard, Emma Ricart Altimiras, Michal Bassani-Sternberg – A microfluidics-enabled automated workflow of sample preparation for MS-based immunopeptidomics – Cell Reports Methods – Volume 3, Issue 6 – 2023 – 100479 – ISSN 2667-2375
Christian Thoben, Nora T. Hartner, Moritz Hitzemann, Christian-Robert Raddatz, Manuel Eckermann, Detlev Belder, and Stefan Zimmermann – Regarding the Influence of Additives and Additional Plasma-Induced Chemical Ionization on Adduct Formation in ESI/IMS/MS – Journal of the American Society for Mass Spectrometry 2023 34 (5), 857-868
Ortiz-Perez A, van Tilborg D, van der Meel R, Grisoni F, Albertazzi L. – Machine learning-guided high throughput nanoparticle design – ChemRxiv. 2023
AMF understands that every application is unique, and off-the-shelf solutions may not always meet specific requirements. That’s why we offer a range of customization options for our microfluidic distribution valves to ensure they fit perfectly into your setup, no matter the complexity of your project.
We collaborate closely with our customers to adapt our valves to different needs, from adjusting port configurations to selecting the ideal materials for enhanced chemical compatibility. Whether you are working in pharmaceuticals, biotechnology, or industrial production, AMF’s flexible customization ensures that you get the most efficient and effective solution.
One example of our tailored solution is the custom distribution switch component developed for a customer requiring fast, accurate fluid switching across multiple pathways. This solution featured a custom valve that combines fluid distribution and switching capabilities in one compact unit, reducing system complexity and allowing for more efficient sample handling.
Another example is a custom complex nanoparticle generator system designed to produce high-quality particles for biomedical research. This project utilized a 24-port distribution valve, which allowed for precise control over multiple fluid inputs, ensuring consistent and reproducible nanoparticle synthesis. By integrating our valve, the system achieved high accuracy and minimal cross-contamination, delivering superior results in the production of nanoparticles.
By offering these options, AMF can develop a solution that perfectly matches your project’s demands. Our engineering team works closely with you to assess your needs and design a valve that enhances your system’s efficiency, performance, and reliability.
Microfluidic distribution valves are fundamental components in the precise management of fluid pathways across various scientific and industrial applications. Their ability to control and route multiple fluid streams efficiently has revolutionized fields such as diagnostics, pharmaceuticals, environmental monitoring, and chemical processing. Whether integrated into compact lab-on-a-chip systems or large-scale instrumentation, these valves enable real-time fluid handling with unparalleled precision.
Microfluidic distribution valves offer critical functionality across numerous real-world applications, ensuring efficient, accurate, and controlled fluid management.
AMF’s microfluidic valves are not just components; they are integral tools for optimizing fluidic management across a wide range of applications. The flexibility, reliability, and efficiency of our valves can dramatically enhance the performance of your systems.
Our valves within our components (RVM or SPM) are designed to seamlessly integrate into existing platforms, allowing for rapid deployment and easy maintenance. From custom port configurations to durable material options, AMF offers tailored solutions that meet the specific needs of each project. By minimizing downtime, reducing fluid waste, and enabling precise control, our valves provide long-term value and support for your evolving applications.
Optimizing your fluidic management with AMF valves means you’ll benefit from:
To explore how AMF can help you optimize fluidic management for your project, please fill out the form below to get in touch with our team. We are eager to discuss your specific needs and provide detailed information on how our valves can improve your fluid handling systems.
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