High-Precision Nanoparticle Formulation Enabled
Oct 2023

High-Precision Nanoparticle Formulation Enabled: A New Era in Microfluidic Research

We extend our heartfelt congratulations to Ana Ortiz-Perez, an TU-Eindhoven researcher, and her team who are pushing the boundaries in the interdisciplinary fields of microfluidics, machine learning, and nanoparticle technology. Her latest paper, “Machine learning-guided high throughput nanoparticle design,” is a work that promises to redefine how we approach nanoparticle research and its applications in medical science.

Leveraging Machine Learning in Nanoparticle Design


The paper is a standout accomplishment in the academic landscape, offering an example of the innovative use of machine learning algorithms for the high-throughput design of nanoparticles. It specifically focuses, as a proof of concept, on the development of PLGA-PEG nanoparticles optimized for high cellular uptake in human breast cancer cells. This research is not just a milestone in nanoparticle technology but also a leap forward in the challenges of targeted drug delivery systems, personalized medicine, and cancer treatment.

How Advanced Microfluidics’ LSPone Enabled Precision and Control in Nanoparticle Formulation


The methodology employed in this research was nothing short of extraordinary, thanks in part to the capabilities of the LSPone Laboratory Syringe Pump. The pump was used to manage a microfluidics device that features a Y-junction geometry and hydrodynamic flow focusing (HFF). This high-precision setup allowed for meticulous control over fluid dynamics and flow rates, thereby facilitating the rapid and highly accurate formulation of nanoparticles. The LSPone’s capabilities were further amplified by our user-friendly and intuitive LSPoneQuick software, which allowed for automation of the manual operational processes and data collection.

The Multifaceted Versatility of the LSPone: A Cornerstone in Modern Microfluidic Research

The LSPone is far more than just a high-precision syringe pump; it’s a versatile, automated, multi-functional tool engineered to meet the diverse needs of microfluidic academic setups. Whether it’s aspirating or dispensing liquids, controlling or automating complex flow rates, preparing intricate liquid mixes, or diluting samples and reagents, the LSPone does it all. Its state-of-the-art design is complemented by the LSPoneQuick software, offering a range of functionalities that empower researchers to conduct more complex and varied experiments.

Immerse Yourself in the Future of Microfluidics and Nanoparticle Research

For anyone deeply interested in the rapidly evolving fields of machine learning, microfluidics, and nanoparticle design, we strongly encourage you to delve into this academic paper. It offers invaluable insights into how high-precision dosing systems like the LSPone are revolutionizing microfluidic research and paving the way for future innovations.

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