Advanced Industrial Microfluidic Rotary Valve - RVM | AMF

RVM – Industrial Microfluidic Rotary Valve

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Discover the new standard in microfluidic rotary valves with our state-of-the-art rotary valve module (RVM) designed for demanding industrial microfluidic applications. The device stands unmatched in the market for its low internal volume, reliability and precise handling, bringing groundbreaking solutions to your laboratory and research, thus paving the way towards industrial microfluidics.

Industrial Microfluidic Rotary Valve (RVM) by AMF

AMF’s RVMs are suited for microfluidics, by design:

  • Microfluidic Valve Design: Choose from a range of valve functions (distribution, switch, On/Off) that ensure no leakage, no dead volume and low carryover volume, offering superior control in microfluidic systems.
  • Wetted Material: The rotary valve’s wetted material is PCTFE (for the valve head) and PTFE (valve rotor) ensuring robustness and broad chemical compatibility.
  • Channel Diameter: 500 µm to 1000 µm. The conjunction of small internal channel size with the unique AMF geometry allows it to reach extremely low internal volumes which can be as low as 600 nL*. This particular attribute optimizes your operation time, saves material (reagents, test materials and samples) and leads ultimately to reduced cost of operations for your final microfluidic application or instrument.
  • Number of Ports: up to 24 radial ports. The valve’s number of ports will give you the ability to handle multiple fluids (up to 24) within your microfluidic instrument (or detection chamber) and/or manipulate multiple fluids (sample to be tested, reagents, gases).
  • Motor Type: Decide between a fast motor for quickly switching applications and a low-power model for reduced energy consumption.

Advanced Microfluidics unique microfluidic rotary valve design:

  • Integrated sensor: the position sensor is directly integrated into the valve rotor (2) to ensure precise valve positioning and internal channel alignment between the rotor (2) and the stator (1) . An automatic procedure at power-up alerts the valve of its precise location.
  • For your motor, choose between the fast model for a port switching speed as low as 150ms (180 degrees) and the low power model to reduce power consumption for better portable device integration and smaller power supply.
  • Easy to use: the valve head (stator (1) + rotor (2)) can be easily removed and exchanged for preventive maintenance services. Our RVM is designed to be compatible with standard connectors widely used in microfluidics and beyond.

Our RVM, as an OEM component, is ideally suited for industrial applications, designed for seamless integration into various systems. Tailored for those looking to incorporate robust microfluidic components into their setups, our versatile RVM can be customized to meet specific requirements, ensuring optimal performance in mass production environments. It supports diverse connective and communication needs, enhancing efficiency and scalability in industrial microfluidic applications.

*Our unique precise valves exhibit an internal volume (port-to-port) down to 600 nL (for a 4 ports switch valves) due to their exceptionally small 0.25 mm diameter channels.

More details

Enhance your expertise with our Application Notes, focused on microfluidic technology utilization:

Samples preparation for online liquid analysis with chemical reaction.

Microfluidic flow cytometry application for bacteria online monitoring in drinking water using BactoSense technology


Gain further insights with detailed guides on:

For comprehensive information, visit our technical notes page.

Discover how our RVM rotary valve is advancing research across various fields. Explore the most recent publications where the rotary valve precision and reliability have been pivotal:

Xiaokang Li, Hui Song Pak, Florian Huber, Justine Michaux, Marie Taillandier-Coindard, Emma Ricart Altimiras, Michal Bassani-Sternberg – A microfluidics-enabled automated workflow of sample preparation for MS-based immunopeptidomics – Cell Reports Methods – Volume 3, Issue 6 – 2023 – 100479 – ISSN 2667-2375

Maël Arveiler, Stephanie Ognier, Olivier Venier, Laurent Schiob and Michael Tatoulian – An innovative sequential flow platform for automated multi-step chemical processes – proof of concept with the separation of amine/alkene model mixtures – Reaction Chemistry & Engineering – Issue 11, 2023

For more comprehensive details or to explore older publications featuring our RVM, please don’t hesitate to contact us.

Model & motor specifications

Reference Configuration Power Weight Dimensions Min. Switching time 180° PCB functionalities
P200-O Low power motor 5-10 VDC, 0.5 A peak 250 g 29 x 38.3 x 111.8 mm 1.5 s Driver, Encoder
P201-O Fast motor 18-24 VDC, 2 A peak 450 g 42.3 x 60 x 95.9 mm 400 ms Driver, Encoder
P211-O Fast motor 18-24 VDC, 2 A peak 450 g 42.3 x 60 x 95.9 mm 400 ms Encoder

Other specifications

Operating temperature 15 – 40°C (59-104°F)
Operating humidity 20-80%, non condensing
Max. pressure 7 bars (102 psi)
Wetted materials PTFE or UHMW – PE, PCTFE
Channel diameter 0.5 mm (0.020 in) or 1 mm (0.039 in) (other upon request)
Internal volume 2.5 – 13.7 μL port-to-port (configuration dependent)
Carryover volume 0.55 – 6.7 μL port-to-port (configuration dependent )
Dead volume None
Tube port fittings Standard 1/4 – 28 UNF, flat-bottom
Electrical interface USB mini, 9–pin D–Sub (fast motor model only)
Communication type Serial, I2C (other upon request)

Valve specifications

Ref. Configuration Wetted materials Internal volume Carryover volume Fluid path diameter Max. pressure
V–D–1–6–050–C–P 6 ports low carryover volume PCTFE, PTFE 2.5 μL 1.5 μL 0.5 mm 7 bars
V–D–1–8–050–C–P 8 ports low carryover volume PCTFE, PTFE 2.5 μL 1.5 μL 0.5 mm 7 bars
V–D–1–8–100–C–P or U 8 ports low carryover volume PCTFE, PTFE or UHMW–PE 13.8 μL 6.7 μL 1 mm 7 bars
V–D–1–10–050–C–P or U 10 ports low carryover volume PCTFE, PTFE or UHMW–PE 3.5 μL 1.7 μL 0.5 mm 7 bars
V–D–1–10–100–C–P or U 10 ports low carryover volume PCTFE, PTFE or UHMW–PE 13.8 μL 6.7 μL 1 mm 7 bars
V–D–1–12–050–C–P or U 12 ports low carryover volume PCTFE, PTFE or UHMW–PE 3.5 μL 1.7 μL 0.5 mm 7 bars
V–D–1–24–050–K–P 24 ports low carryover volume PEEK, PTFE 3.6 μL 2.2 μL 0.5 mm 7 bars


Ref. Configuration Wetted materials Internal volume Carryover volume Fluid path diameter Max. pressure
V–O–1–2–050–C–P 2 ports PCTFE, PTFE 3.0 μL - 0.5 mm 7 bars


Ref. Configuration Wetted materials Internal volume Carryover volume Fluid path diameter Max. pressure
V–S–1–4–050–C–P 4 ports ultra-low carryover volume PCTFE, PTFE 2.8 μL 0.8 μL 0.5 mm 7 bars
V–S–1–6–050–C–P 6 ports ultra-low carryover volume PCTFE, PTFE 2.5 μL 0.6 μL 0.5 mm 7 bars

Valve heads are interchangeable. Other models available upon request.

AMF valves meet our needs, particularly in terms of control

Bernard Roux - Lab manager Solvay

AMF’s compact products and expert support boost microfluidics

Hana Samet - Engineer AGORA & EPFL Research Center

We are highly content with our AMF rotary valves’ performance

Maarten Jorna - Mechanical engineer The Sensor Factory

Custom AMF components allowed us to develop the first online flow cytometer for water monitoring

Simon Kuenzi - CEO bNovate

AMF’s products automate microfluidics with precise control and timely support

Xiaokang LI - Postdoctoral researcher Department of Oncology UNIL CHUV Ludwig Institute for Cancer Research Lausanne Centre de recherche Agora

AMF valves, delicately designed, reflect Swiss precision

Yujing Song - PhD Michigan Univeristy

FAQ: Mastering the RVM - Industrial Microfluidic Electric Rotary Valve

Dive into our comprehensive FAQ section to gain deeper insights into the RVM Industrial Microfluidic Electric Rotary Valve. Designed for precision and efficiency, our RVM valve is a cornerstone of advanced fluidic systems. Here, we address your most pressing queries, from technical specifications to integration details. Explore how the RVM valve’s innovative design, Swiss-engineered precision, and versatile functionality can revolutionize your microfluidic applications, enhancing both laboratory and industrial processes. Whether you’re a seasoned engineer or new to the field, our FAQ is your gateway to understanding the full potential of our state-of-the-art RVM valve.

The RVM microfluidic electric rotary valve is unique in having no dead volume. This feature ensures efficient fluid handling and minimal waste in lab systems, critical for precision in microfluidic applications. The absence of dead volume in the valve is crucial for avoiding unnecessary fluid loss and contamination, enhancing the reliability and accuracy of fluid handling in various lab systems.

The RVM valve’s carry-over volumes range from 0.55 to 6.7 µL, depending on configuration. This low carry-over volume minimizes the risk of cross-contamination and preserves sample integrity in microfluidic applications. In systems where precise fluid handling is essential, such as in sample testing and reagent mixing, this feature of the RVM valve ensures accuracy and reliability, making it an ideal choice for sensitive and high-precision microfluidic applications.

The RVM device’s internal volume is remarkably low, potentially as low as 600 nL. This low internal volume is significant in high-pressure flow applications as it optimizes operation time and reduces operational costs. The small internal volume is particularly beneficial in applications where precision and minimal fluid use are vital, such as in the handling of expensive reagents or in applications where the volume of available sample is limited.

The RVM valve’s design, with up to 12 ports and compatibility with standard connectors, facilitates seamless integration with existing microfluidic systems. This adaptability makes it ideal for lab-on-a-chip applications, where space and efficiency are critical. The valve’s ability to handle multiple fluidic paths simultaneously and its compatibility with various system configurations underscore its role as a versatile and essential component in modern microfluidic technology.

The average lead time for the RVM valve is around 4 weeks, although this may vary based on the specific configuration required. This efficient lead time, coupled with the valve’s quick switching capabilities and precise control, greatly facilitates rapid system integration in lab settings. The RVM’s design, focused on minimizing operational delays and enhancing fluid handling efficiency, ensures that it can be quickly and effectively incorporated into various microfluidic applications, thus accelerating the deployment of lab systems and research endeavors.

The RVM valve’s sealing mechanism is uniquely designed to ensure minimal leakage, crucial in fluid handling applications. This precision is achieved through high-quality manufacturing processes where the valve is meticulously machined in production workshops in Switzerland using CNC technology. This level of precision and quality inherent in Swiss manufacturing practices ensures that the valves are crafted with exceptional accuracy, effectively eliminating leaks. Consequently, this contributes to superior control in fluid handling and maintains the integrity of fluidic applications, reinforcing the RVM valve’s reputation for reliability and efficiency in various microfluidic settings.

The RVM valve’s switching mechanism, featuring a fast motor model, provides port switching speeds as low as 150ms. This quick switching capability is critical for microfluidic devices that require precise fluid control, such as in high-throughput screening or automated testing setups. The ability to switch rapidly between ports without sacrificing accuracy or control makes the RVM valve an invaluable tool in applications where timing and precision are of the essence.

The incorporation of an electric motor in the RVM valve allows for fast and precise switching between fluidic paths. This is especially beneficial in micromachines and small-scale systems where space is limited and efficiency is paramount. The electric motor’s precision contributes to reduced operation time and increased efficiency, making the RVM valve an ideal choice for sophisticated microfluidic devices that demand quick and accurate fluid handling.

The RVM valve, with its low internal volume and precise control, plays a significant role in efficient sample handling and testing in microfluidic channels and systems. This precision is crucial in applications involving sensitive or limited samples, as it ensures minimal waste and maximizes the accuracy of the results. The valve’s ability to accurately control fluid flow makes it an essential component in lab setups, particularly in analytical and diagnostic applications.

The RVM valve stands out as a particularly suitable choice for applications that demand high flow rates combined with minimal port leakage. This efficiency is rooted in its advanced design, which is optimized to handle substantial fluid volumes swiftly and effectively. Additionally, the precision engineering of the RVM valve, with its meticulous attention to detail in manufacturing, ensures that port leakage is minimized. This aspect is critical in high-performance fluidic applications where maintaining the integrity of the fluid path and preventing cross-contamination are paramount. The valve’s capability to manage high flow rates without compromising on leakage prevention makes it an ideal solution for demanding microfluidic systems, where both high throughput and accuracy are essential.

The RVM valve plays a pivotal role in integrated microfluidic systems, primarily due to its versatility and precision. The valve’s design, offering multiple port options, allows for the simultaneous management of various fluidic paths, essential in complex microfluidic setups. This multi-port functionality enables the integration of diverse fluidic operations, from sample processing to reagent handling, within a single system. Additionally, the RVM valve’s precise control capabilities ensure accurate fluid distribution and regulation, which is crucial for maintaining consistency and reliability in experiments and processes. This precise control translates to enhanced overall system performance, reducing errors and improving the reproducibility of results. In essence, the RVM valve’s integration into microfluidic systems significantly boosts their efficiency and effectiveness, making it a key component in advancing the capabilities of modern laboratory and industrial microfluidic applications.

The RVM valve’s design is meticulously tailored to ensure seamless compatibility with a diverse range of fluidic elements and parts commonly used in lab environments. Key to this adaptability are the materials used in its construction: PTFE or UHMW – PE, and PCTFE. These materials are known for their robustness and broad chemical compatibility, making the valve suitable for various applications. Additionally, the valve features a standard 1/4 – 28 UNF, flat-bottom tube port fitting, which is a common specification in microfluidics, ensuring easy integration with existing systems. The electrical interface of the valve, which includes options like USB mini and a 9–pin D–Sub for the fast motor model, further enhances its versatility. Moreover, the valve supports various communication types, including Serial and I2C, allowing for flexible and straightforward integration into diverse electronic control systems. Together, these design elements make the RVM valve highly adaptable and efficient in a range of lab settings, ensuring compatibility with a wide array of fluidic components and systems.

The RVM valve excels in providing precise control over fluid channels and selectors, which is vital in fluidic applications that demand detailed fluid manipulation. This precision is key in applications such as drug discovery, where the accurate delivery and mixing of fluids can impact the outcome of experiments. The valve’s design enables exact control over fluid flow, ensuring precise and reproducible results in various microfluidic applications.

The RVM valve’s design, featuring up to 12 ports, enables it to handle complex fluidic setups, crucial in high-performance fluid handling applications. This multi-port functionality allows for the integration of additional ports and channels, facilitating complex assays and processes in advanced microfluidic systems. The valve’s versatility in managing multiple fluidic paths simultaneously makes it a valuable asset in sophisticated lab environments and industrial applications.

The RVM valve’s innovative design, characterized by its low internal volume and precision control, aligns with the latest advancements in microfluidics. This innovation is reflected in its potential impact on industrial applications and its relevance to current research, as highlighted in publications and articles like those found on PubMed. The valve’s cutting-edge features make it a topic of interest in the scientific community, with its capabilities pushing the boundaries of what’s possible in microfluidic technology.

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From top-tier academic institutions to pioneering biotech companies, Advanced Microfluidics is the preferred partner for innovative microfluidic solutions. Our track record of excellence and precision has earned us the trust of industry leaders, driving us to push boundaries and redefine possibilities together.

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