New SPM Edition: Ultra-Low Flow Rates for Precision Fluid Control
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Feb 2025

Introducing the new SPM: Enhanced low-flow rate for higher precision and versatility

At AMF, we’re always pushing the boundaries of precision and reliability in fluid dispensing. That’s why we’re excited to introduce the latest iteration of our industrial programmable syringe pump (SPM)—a revolutionary upgrade with a new low-flow rate edition. This new SPM brings an extraordinary advancement: it offers a flow rate that’s 134 times lower than its predecessor, enabling even more precise fluid control for a wide range of applications.

This enhanced low-flow rate capability transforms how fluids are delivered, making it perfect for applications that demand slow, consistent, and highly controlled fluid infusion. From precise drug infusions to long-term biological studies, this new version of the SPM is designed to handle the most demanding requirements with unmatched accuracy. In this article, we’ll walk you through the key features of this new SPM edition, how it outperforms previous models, and how it opens up exciting possibilities across various industries.

A new low-flow rate edition for exceptional precision

One of the most exciting features of this new SPM iteration is its incredible ability to achieve ultra-low flow rates. With the introduction of this new flow rate edition, the SPM can now deliver fluid at rates that are 134 times lower than what was previously possible. For example, this version supports peak speeds as low as 74.5 nm/s (74,5 nL / min), a significant reduction from the 500 nm/s capability of the previous model.

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This ultra-low flow capacity offers unparalleled precision in fluid dispensing, making it ideal for highly sensitive applications. Whether you’re conducting perfusion studies, performing microfluidic research, or controlling drug delivery, this new SPM provides the accuracy and reliability you need. The ability to achieve such low flow rates also ensures improved control over the fluid process, even for the smallest volumes.

Flow rate examples using the new low-flow rate SPM

To highlight the impact of this new SPM iteration, let’s look at some real-world examples of how the new low-flow rate capability compares with previous models, using data from the SPM’s plunger speeds and syringe sizes.

1. Plunger Speed: 7.45 µm/s

  • Syringe Size 50 µL
  • Flow Rate: 0.00745 µL/min

This ultra-low plunger speed ensures incredibly slow and controlled fluid dispensing. It’s perfect for tasks that require precise micro-dispensing over extended periods, such as in long-term biological studies or microfluidic applications.

2. Plunger Speed: 50 µm/s

  • Syringe Size 100 µL
  • Flow Rate: 0.1 µL/min

With this flow rate, the SPM delivers more fluid but still at a very precise, controlled rate. This is ideal for infusion processes where small but consistent amounts of fluid need to be delivered over an extended time, such as in drug infusion studies or cell perfusion experiments.

3. Plunger Speed: 500 µm/s

  • Syringe Size 500 µL
  • Flow Rate: 50 µL/min

At this speed, the SPM handles higher flow rates while still maintaining precision. This makes it well-suited for applications requiring longer, continuous fluid delivery, such as in pharmaceutical testing or automated chemical reactions.

4. Plunger Speed: 10,000 µm/s

  • Syringe Size 1 mL
  • Flow Rate: 100 µL/min

This moderate flow rate is perfect for applications that need more fluid delivered quickly but still with precision. For example, this can be used in enzyme kinetics or metabolic studies where consistent fluid delivery is crucial.

5. Plunger Speed: 50,000 µm/s

  • Syringe Size 1,000 µL
  • Flow Rate: 1000 µL/min

This high-speed setting allows for rapid fluid transport, making it ideal for tasks requiring quick fluid delivery, such as chemical manufacturing processes or automated sampling systems.

Summary of key flow rates for example syringe sizes:

 

Plunger Speed (µm/s) Motor Speed (pulses/s) Syringe Size
Flow Rate (µL/min)
7.45 0.00745 50 µL 0.00745 µL/min
7.45 0.00745 100 µL 0.0149 µL/min
7.45 0.00745 250 µL 0.03725 µL/min
7.45 0.00745 500 µL 0.0745 µL/min
7.45 0.00745 1,000 µL 0.149 µL/min
50 0.05 50 µL 0.05 µL/min
50 0.05 100 µL 0.1 µL/min
50 0.05 250 µL 0.25 µL/min
50 0.05 500 µL 0.5 µL/min
50 0.05 1,000 µL 1 µL/min
500 5 50 µL 5 µL/min
500 5 100 µL 10 µL/min
500 5 250 µL 25 µL/min
500 5 500 µL 50 µL/min
500 5 1,000 µL 100 µL/min
10 50 50 µL 10 µL/min
10 50 100 µL 20 µL/min
10 50 250 µL 50 µL/min
10 50 500 µL 100 µL/min
10 50 1,000 µL 200 µL/min
50 250 50 µL 50 µL/min
50 250 100 µL 100 µL/min
50 250 250 µL 250 µL/min
50 250 500 µL 500 µL/min
50 250 1,000 µL 1,000 µL/min
100 500 50 µL 100 µL/min
100 500 100 µL 200 µL/min
100 500 250 µL 500 µL/min
100 500 500 µL 1,000 µL/min
100 500 1,000 µL 2,000 µL/min
150 750 50 µL 150 µL/min
150 750 100 µL 300 µL/min
150 750 250 µL 750 µL/min
150 750 500 µL 1,500 µL/min
150 750 1,000 µL 3,000 µL/min


 

Key benefits of the new low-flow rate edition:

1. Improved flow rate control:

The most significant benefit of this new low-flow rate edition is the enhanced control over the flow process. This gives researchers and engineers the ability to adjust fluid delivery with unmatched precision, allowing for more accurate experimental results across a range of applications.

2. Precision in data collection at minimal flow rates:

Many experiments require extremely low flow rates to gather accurate data. With the new SPM edition, researchers can now collect data at ultra-low speeds with much greater consistency, which is critical for high-precision experiments in fields like microfluidics and biological research.

3. Improved control in infusion processes:

The enhanced low-flow capabilities make the SPM ideal for infusion applications in fields like biotechnology, pharmaceuticals, and medical research. The ability to control fluid delivery down to extremely low flow rates ensures that experiments or treatments can be carried out with the necessary precision and without fluctuation.

Applications benefiting from the new low-flow rate edition

This new SPM iteration opens up a variety of possibilities where precise fluid control is critical. Here are some key applications that benefit from this enhanced capability:

  • Infusion applications: In pharmaceutical research, patient care, or bioengineering, the ability to control fluid infusion with ultra-low flow rates is vital. The new SPM allows precise infusion of drugs, nutrients, or other fluids, ensuring that the correct volume is delivered consistently over time. This is crucial for drug development and clinical studies where small but accurate fluid volumes must be administered.
  • Microfluidics and lab-on-a-chip systems: The SPM’s low flow rate is ideal for microfluidic applications, where controlling tiny amounts of fluid is essential. From chemical reactions to cell assays, this new SPM allows precise fluid control in microchannels, enabling researchers to perform experiments that require high accuracy.
  • Long-term biological studies and cell culture: Maintaining a steady, minimal flow rate is essential in biological studies and cell culture. The new SPM can provide continuous, ultra-low flow delivery, ensuring that the microenvironment for cells or tissues remains stable over extended periods. This is crucial for perfusion studies, tissue cultivation, or other long-term biological research.
  • Drug development and testing: In drug development, researchers need to deliver precise, controlled doses over extended periods. With the new SPM, you can now conduct microdosing or controlled infusion studies with confidence, knowing that the fluid delivery will be accurate, consistent, and reliable.

Improved precision with enhanced flow rate control

Beyond offering lower flow rates, the new SPM iteration also delivers improved precision in flow rate control. With better resolution between speed and flow rate, the pump ensures that even the smallest changes in fluid delivery are highly controlled. This is crucial in droplet generation, DNA sequencing, or other precision tasks where consistency and accuracy are paramount.

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AMF’s latest SPM edition takes fluid dispensing to a new level of precision with its low-flow rate edition, offering a flow rate that is 134 times lower than the previous version. Whether you’re conducting long-term biological studies, precision microfluidics research, or drug infusion experiments, this enhanced SPM provides the control, accuracy, and reliability needed for even the most demanding tasks.

With a broad range of applications now possible, the new SPM is a powerful tool for researchers, engineers, and professionals in fields requiring ultra-precise fluid delivery. The ability to handle low flow rates and offer improved flow rate control makes this new edition a must-have for those looking to achieve the highest level of accuracy in their work.

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